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The SASInstitute A00-282 exam covers a wide range of topics that are essential for clinical trial programming using SAS 9.4. These topics include the design and implementation of clinical trials, data management and analysis, and the interpretation and reporting of results. A00-282 exam also covers the use of SAS software for data analysis and programming, and the use of industry standards and regulations in clinical trials programming.
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The A00-282 exam is intended for individuals who have a strong background in statistics, as well as experience with SAS programming. Candidates should have a thorough understanding of statistical concepts, including hypothesis testing, regression analysis, and analysis of variance (ANOVA), as well as experience using SAS software for data analysis and reporting.
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SASInstitute A00-282 Certification Exam is designed for individuals seeking proficiency in clinical trials programming using SAS 9.4. Clinical Trials Programming Using SAS 9.4 certification validates the candidate's knowledge and skills in programming techniques, clinical trial data structures, and SAS programming concepts. Clinical Trials Programming Using SAS 9.4 certification is ideal for individuals working in the pharmaceutical, biotechnology, or clinical research industries.
| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Transform or Summarize Clinical Trials Data | 15% | - Data step manipulation - Aggregation and transposition - Derive variables and study days |
| Topic 2: Macro Programming for Clinical Trials | 15% | - Create and call macros - Debugging macros - Macro variables and parameters |
| Topic 3: Regulatory Submissions | 5% | - Compliance for clinical data reporting - ICH and FDA guidelines |
| Topic 4: Clinical Trials Data Structures | 10% | - CDISC standards: SDTM, ADaM - Define.xml and dataset specifications - Clinical domain structures |
| Topic 5: Validate Clinical Trial Data Reporting | 20% | - Programming validation techniques - Validation principles - Use PROC COMPARE and log review |
| Topic 6: Clinical Trials Process | 5% | - Clinical trial lifecycle and protocol - Derive programming requirements from protocol and CRF |
| Topic 7: Report Clinical Trials Results | 10% | - Produce tables, listings, and figures - PROC REPORT and PROC PRINT |
| Topic 8: Manage Clinical Trials Data | 5% | - Access and explore clinical datasets - Clean, merge, and subset data - Use SQL and dictionary tables |
| Topic 9: Apply Statistical Procedures for Clinical Trials | 15% | - PROC MEANS, FREQ, TABULATE - Basic statistical analysis for clinical data |
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