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| Section | Weight | Objectives |
|---|---|---|
| Topic 1: Directing Laboratory Administrative Functions | 19% | - Personnel management, competency assessment and training - Process improvement and risk management - Laboratory operations, budgeting and compliance - Information management and reporting - Accreditation, licensure and regulatory requirements |
| Topic 2: Consulting with Other Medical Professionals | 25% | - Clinical consultation, result interpretation and guidance - Education, research and professional development - Public health, epidemiology and outbreak investigation |
| Topic 3: Ensuring Safety and Security in the Laboratory | 11.5% | - Security, waste management and emergency response - Biological, chemical and physical safety |
| Topic 4: Directing Laboratory Testing Functions | 44.5% | - Up-to-date practices, standards, technologies and emerging diseases - Test selection, validation, quality control and interpretation |
Question 1
A patient with severe combined immunodeficiency (SCID) develops a progressive respiratory illness.
Bronchoalveolar lavage fluid is examined using direct fluorescent antibody (DFA) staining, which reveals numerous cysts of Pneumocystis jirovecii. The cysts appear:
A. Small and round with a thick wall, containing sporozoites.
B. Oval-shaped with a thin wall and internal nuclei.
C. Cup-shaped or helmet-shaped with internal structures.
D. Large and multinucleated with prominent endospores.
Question 2
An acid-fast bacillus isolate recovered from a respiratory specimen after 3 weeks of incubation on Löwenstein- Jensen medium is initially non-pigmented when grown in the dark. After exposure to light for several hours, the colonies develop a distinct yellow-orange pigment. This organism is classified as a:
A. Scotochromogen
B. Rapid grower
C. Photochromogen
D. Nonchromogen
Question 3
A patient with cystic fibrosis experiences a pulmonary exacerbation. Sputum culture grows a mucoid strain of Pseudomonas aeruginosa. The mucoid phenotype is primarily due to the overproduction of:
A. Exotoxin A
B. Pyocyanin
C. Alginate
D. Elastase
Question 4
A clinical laboratory receives a cerebrospinal fluid (CSF) sample from a 65-year-old patient presenting with fever, headache, and nuchal rigidity. Gram stain reveals Gram-positive cocci in pairs and short chains. Culture on blood agar grows alpha-hemolytic colonies that are optochin-susceptible and bile soluble. Which organism is most likely identified?
A. Staphylococcus aureus
B. Streptococcus pneumoniae
C. Streptococcus agalactiae
D. Enterococcus faecalis
Question 5
A patient presents with a pruritic rash consisting of raised, serpiginous tracks on their skin. The patient recently returned from a Caribbean vacation and reported walking barefoot on the beach. The MOST likely causative organism is:
A. Pediculus humanus
B. Larvae of Strongyloides stercoralis
C. Sarcoptes scabiei
D. Larvae of Ancylostoma braziliense
Solutions:
| Question 1 Answer: C | Question 2 Answer: C | Question 3 Answer: C | Question 4 Answer: B | Question 5 Answer: D |
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